RNA based vaccines with tolerability close to the standard of care by dampening an excessive innate immune response
Nucleic acid vaccines have come a long way since their first use in preclinical experiments. Major advances in capping, delivery, manufacturing, and non-natural nucleosides enabled the field to grow.
These solutions, while game-changing, have all focused on engineering the chemistry and delivery of nucleic acids.
ExcepGen's RNAx platform addresses the cellular response to nucleic acids. RNAx is an mRNA encoded protein that alters the way that cells respond to RNA and LNPs by dampening an overactive innate immune response. Read our recent publication here.
Self-amplifying mRNA vaccines
Trans-amplifying mRNA vaccines
mRNA vaccines
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We're a team of visionary scientists unwilling to accept the status quo. Our drive to improve human health wakes us up and motivates our research. We believe that by exploring foundational principles of biology, we can make the greatest impact on human life.
